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More than 70% of the immunoglobulin A in the human body is produced in the intestines.

Metabolic disorders lead to the following health issues.

 

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Diabetes

  • Research from HKUMed suggested that effective blood sugar control is crucial for maintaining antiviral immunity. 8 
  • Cell function and the ability to fight against viruses in diabetic patients is worse than healthy people. 8
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Metabolic 

syndrome

  • Metabolic syndrome such as a large waistline, high blood pressure, high glucose, or high blood lipids—can increase the burden on the immune system or even impair it.
  • It may also lead to various metabolic diseases that can increase the burden on, or damage, the immune system.
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Thyroid dysfunction

  • The thyroid is an important endocrine organ that mainly secretes thyroid hormones to regulate the body’s metabolic rate.
  • A high metabolic rate causes hyperthyroidism, leading to an overactive immune system, feeling overheated, rapid weight loss, and a fast heartbeat.
  • A slow metabolic rate causes hypothyroidism, leading to a weakened immune response, easy swelling, weight gain, and low energy.
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Gut health

  • Metabolic disorders change the intestinal flora, which can easily cause allergies.
  • Affect internal balance, glucose and lipid metabolism, and the immune system.

Learn More


1. HKSAR Gov Department of Health. (2020-2022). Population Healthy Survey

2. Yates KF, Sweat V, Lai YP, et al. Impact of Metabolic Syndrome on Cognition and Brain: A Selected Review of the Literature. Arterioscler Thromb Vasc Biol. 2012; 32(9): 2060–2067. https://doi.org/10.1161/ ATVBAHA.112.252759

3. Levin BE, Llabre MM, Dong C, et al. Modeling metabolic syndrome and its association with cognition: the Northern Manhattan study. J Int Neuropsychol Soc. 2014: 20(10): 951–60. https://doi.org/10.1017/ S1355617714000861

4. Mateusz Siedlinski, Carnevale, L., Xu, X., Carnevale, D., Evangelou, E., Caulfield, M. J., Maffia, P., Wardlaw, J. M., Samani, N. J., Tomaszewski, M., Lembo, G., Holmes, M. V., & Guzik, T. J. (2023). Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure. European Heart Journal, 44(23), 2114–2125. https://doi.org/10.1093/eurheartj/ehad101‌

5. Yaffe K, Vittinghoff E, Pletcher MJ, et al. Early adult to midlife cardiovascular risk factors and cognitive function. Circulation. 2014; 129(15): 1560–7. https://doi.org/10.1161/CIRCULATIONAHA.113.004798

6. *Cavalieri M, Ropele S, Petrovic K, et al. Metabolic Syndrome, Brain Magnetic Resonance Imaging, and Cognition. Diabetes Care. 2010; 33(12): 2489–2495. https://doi.org/10.2337/dc10-0851

7.  #Exalto LG, van der Flier WM, van Boheemen CJ, et al. The metabolic syndrome in a memory clinic population: relation with clinical profile and prognosis. J Neurol Sci. 2015; 351(1–2): 18–23. https://doi. org/10.1016/j.jns.2015.02.004

8.  The LKS Faculty of Medicine of the University of Hong Kong (HKUMed). (2024). High blood glucose weakens immunity against viral infections in type 2 diabetes patients